Figure 6.
Effect of the free radical scavenger tiron and the putative NADPH oxidase inhibitor apocynin on hypoxic vasodilation. Effect of (A) the free radical scavenger tiron (10 μM) and (B) the putative NADPH oxidase inhibitor, apocynin (10 μM) on concentration-response curves for oxygen lowering in coronary arterial segments contracted with PGF2α (10 μM). Results are means ± SEM of 8-9 experiments. Differences were evaluated with two-way ANOVA with Bonferroni post-test: * P < 0.05, ** P < 0.01, ***P < 0.001 compared to control.