Table 2.
Genotype and survival
| Progression-free survival | Overall Survival | |||||
|---|---|---|---|---|---|---|
| SNP and Genotype | Median (months) | HR | p | Median (months) | HR | p |
| XRCC1:rs25487 | ||||||
| AA or AG | 31.5 | 1.4 | 0.41 | 23.7 | 0.86 | 0.66 |
| GG | NR (>38) | 49.3 | ||||
| XRCC2:rs6464628 | ||||||
| GG or GA | 22.9 | 1.6 | 0.24 | 53.5 | 1.3 | 0.52 |
| AA | NR (>31.5) | 46.7 | ||||
| ERCC1:rs3212986 | ||||||
| GT or TT | 37.9 | 1.1 | 0.78 | 46.7 | 0.96 | 0.90 |
| GG | NR (>31.5) | 35.0 | ||||
| XPD:rs13181 | ||||||
| GG or GT | 46.5 | 0.63 | 0.25 | 46.7 | 0.67 | 0.27 |
| TT | 16.0 | 21.0 | ||||
| XPD:rs1799793 | ||||||
| AA or AG | NR (>40) | 0.80 | 0.57 | NR (>40) | 0.59 | 0.14 |
| GG | 31.4 | 21.0 | ||||
HR, hazard ratio; NR, not reached; SNP, single nucleotide polymorphism.