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. 2011 Jun 1;12:34. doi: 10.1186/1471-2172-12-34

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Copyright ©2011 Ponte et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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IL-10 production by peripheral blood cells from individuals with positive or negative skin prick test (SPT) reactions to B. tropicalis extract (BtE), as indicated in the x-axis. Whole blood cells were assessed for their capacity of producing IL-10 in vitro either when non-stimulated (-) or when stimulated with BtE, A. lumbricoides extract (AlE), pokeweed mitogen (PWM) or bacillus Calmette-Guérin lysate (BCG), as indicated in the top of the figure. Columns represent the mean IL-10 concentrations in the supernatants of cultures from 12 individuals with negative SPT reaction to BtE or from 19 individuals with positive SPT reaction to BtE. Vertical bars represent the standard deviations of the means. No statistically significant differences were found between the negative SPT and the positive SPT groups for any of the tested stimulants (p > 0.05, Mann-Whitney U test).