Table 2.
Combination of experiments and time points to create the 4 main responses to mastitis infection
Time after infection | ||||||||
---|---|---|---|---|---|---|---|---|
Experiment # | 2 h | 3 h | 6 h | 8 h | 12 h | 24 h | 36 h-72 h | 72 h |
1A: E. coli in cattle (in vivo) | {1} I, II, IV |
{2} I, IV |
{3} I, III, IV |
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1B: S. aureus in cattle (in vivo) | {4} I, IV |
{5} I, IV |
{6} I, II, IV |
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1C: S. aureus in cattle (in vivo) | {7} I, II, IV |
{8} I, III, IV |
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2: S. uberis in cattle (in vivo) | {9} I, IV |
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3: S. aureus in cattle macrophages (in vitro) | {10} I, II, IV |
{11} I, III, IV |
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4: S. aureus in goat (in vivo) | {12} I, II |
{13} I, III |
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5: S. aureus in sheep dendritic cells (in vitro) | {14} I, II |
{15} I, III |
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6: S. aureus in goat (in vivo) | {16} I |
Combination of microarray data from a total of 6 different experiments and 16 different time points ({in parentheses}, see also Table 1 and text for details) to analyse 4 different responses to mastitis infection: (I) overall response, (II) early stage response, (III) late stage response, and (IV) cattle-specific response.