Table 1.

Relative proportions of rAAV genomes with free tail-ends and with various tail-end junctions in SCID mice

	%
	18 weeks	52 weeks
Free ends (2.9 kb, from HindIII)	23.5	1.0
Tail-to-tail (5.8 kb, from HindIII)*	12.3	2.2
Head-to-tail (3.7 kb, from HindIII)	18.9	4.5
Vector–cellular genome (deduced)	(45.3)	(92.3)
Total copies of vectors† (internal fragments, from BglII or ScaI)	100	100

^*Two copies of vector genomes in each junction. 

^† The internal fragments were taken as an index of the total copies of rAAV genomes.