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. 2001 Mar 20;98(7):4089–4094. doi: 10.1073/pnas.061031898

Figure 2.

Figure 2

Effects of LeTx on anchorage independent colony formation and extracellular matrix invasion. We evaluated the ability of V12 H-ras-transformed cells to form colonies in Noble agar (a and b) or invade Matrigel (c and d) in the presence (b and d) or absence (a and c) of LeTx. (e) Levels of cathepsin L were assayed by immunoblotting lysates of V12 H-ras-transformed NIH 3T3 cells which had been treated with medium alone, PA plus inactive LF(E687C), or LeTx. Blots were stripped and reprobed with antibodies raised against β-tubulin to control for lane loading.