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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Nat Struct Mol Biol. 2011 Mar 27;18(4):423–431. doi: 10.1038/nsmb.2038

Figure 7. Topologically equivalent signature helices connect nucleotide binding to conformational changes in the ABC-ATPase superfamily.

Figure 7

Rad50 ABC-ATPase molecular surface with attached coiled-coil and mapped Mre11 RBD compared to MalK ABC-ATPase with interacting MalF transmembrane protein. The extended signature helix (purple) and signature coupling helices or helix (cyan) connect nucleotide binding to movements of attached functional domains and proteins.