Table 5.
Semiquantitative Evaluation of VCAN and EGFR Immunostaining in Human Endometrial Tissue Sections From Women With Mild And Severe Endometriosis, As Well As Without Endometriosis
Protein | PE Mild Endometriosis |
ESE Mild Endometriosis |
MSE Mild Endometriosis |
PE Severe Endometriosis |
ESE Severe Endometriosis |
MSE Severe Endometriosis |
||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Epithelium | Stroma | Epithelium | Stroma | Epithelium | Stroma | Epithelium | Stroma | Epithelium | stroma | Epithelium | Stroma | |
EGFR | + | ++ | + | +/++ | ++ | ++ | ++ | ++ | + | +++ | ++ | ++ |
VCAN | −/+ | +++ | ++ | + | ++ | ++ | +++ | + | ++ | + | +++ | ++ |
PE no endometriosis |
ESE no endometriosis |
MSE no endometriosis |
||||||||||
Epithelium |
Stroma |
Epithelium |
Stroma |
Epithelium |
Stroma |
|||||||
EGFR | ++ | ++ | + | + | ++ | + | ||||||
VCAN | ++ | + | +/++ | + | ++ | + |
Abbreviations: PE, proliferative phase endometrium; ESE, early secretory phase endometrium; MSE, mid-secretory endometrium; VACN, versican; EGFR, epidermal growth factor receptor; −, no staining, −/+, a few stained cells; +, faint staining; ++, moderate staining; +++, strong staining.