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. Author manuscript; available in PMC: 2012 May 1.

Published in final edited form as: Basic Res Cardiol. 2011 Feb 2;106(3):473–483. doi: 10.1007/s00395-011-0155-2

Table 3.

Proinflammatory cytokines in the PVN and plasma (n = 7)

Measurements at 4 weeks	PVN (pg/mg protein)			Plasma (pg/ml)
Measurements at 4 weeks	TNF-α	IL-1β	IL-6	TNF-α	IL-1β	IL-6
HF + NBI-27914	3.9 ± 0.4^†	20.2 ± 2.7^†	25.2 ± 2.4^†	14.4 ± 1.3^†	63.4 ± 6.1^†	41.5 ± 4.3^†
HF + vehicle	7.2 ± 0.6^*	50.2 ± 4.9^*	63.2 ± 6.0^*	34.1 ± 3.3^*	112.5 ± 10.2^*	94.5 ± 9.2^*
SHAM + NBI-27914	3.2 ± 0.4	17.9 ± 1.6	20.3 ± 1.9	11.2 ± 1.2	54.3 ± 4.7	34.2 ± 3.8
SHAM + vehicle	3.4 ± 0.4	19.1 ± 2.4	23.4 ± 2.0	12.5 ± 1.2	58.4 ± 5.2	38.3 ± 4.1

^*

P < 0.05 versus SHAM + NBI-27914 or SHAM + vehicle;

^†

P < 0.05 HF + NBI-27914 versus HF + vehicle