Table 2.
BabA-H | BabA-L | BabA negative | |||
---|---|---|---|---|---|
babA gene | + | + | + | ||
BabA protein | + | weak | − | Lebbinding as gold standard |
|
Leb binding | + | − | − | Sensitivity, % | Specificity, % |
Colombia and Japan | n = 68 | n = 8 | n = 4 | ||
Primer pair A | 29 | 5 | 0 | 43 | 58 |
Primer pair B | 38 | 8 | 0 | 56 | 33 |
Primer pair C | 55 | 8 | 0 | 81 | 33 |
Primer pair D | 46 | 8 | 0 | 68 | 33 |
Primer pair A–D | 61 | 8 | 0 | 90 | 33 |
Colombia | n = 33 | n = 3 | n = 4 | ||
Primer pair A | 12 | 0 | 0 | 36 | 100 |
Primer pair B | 15 | 3 | 0 | 45 | 57 |
Primer pair C | 26 | 3 | 0 | 79 | 57 |
Primer pair D | 26 | 3 | 0 | 79 | 57 |
Primer pair A–D | 30 | 3 | 0 | 91 | 57 |
Japan | n = 35 | n = 5 | n = 0 | ||
Primer pair A | 17 | 5 | — | 49 | 0 |
Primer pair B | 23 | 5 | — | 66 | 0 |
Primer pair C | 29 | 5 | — | 83 | 0 |
Primer pair D | 20 | 5 | — | 57 | 0 |
Primer pair A–D | 31 | 5 | — | 89 | 0 |