Table 6.
Final Model Using Multiple Linear Regression Analysis: H pylori Factors Associated With Histology
Pathology | Sites | Factors | Partial regression coefficient ± SE |
P value | Multiple correlation coefficient |
---|---|---|---|---|---|
Western countries | |||||
H pylori density | Antrum | BabA (L vs H) | 0.77 ± 0.29 | .022 | 0.35 |
BabA (H vs negative) | 0.12 ± 0.25 | ||||
BabA (L vs negative) | 0.89 ± 0.36 | ||||
Corpus | cagA (positive vs negative) | 0.62 ± 0.25 | .013 | 0.43 | |
BabA (L vs H) | 0.71 ± 0.20 | .019 | |||
BabA (H vs negative) | −0.01 ± 0.31 | ||||
BabA (L vs negative) | 0.70 ± 0.37 | ||||
Neutrophil infiltration | Antrum | BabA (L vs H) | 0.54 ± 0.35 | .012 | 0.41 |
BabA (H vs negative) | 0.76 ± 0.30 | ||||
BabA (L vs negative) | 1.30 ± 0.45 | ||||
Corpus | BabA (L vs H) | 0.62 ± 0.31 | <.001 | 0.27 | |
BabA (H vs negative) | 0.84 ± 0.26 | ||||
BabA (L vs negative) | 1.46 ± 0.39 | ||||
Atrophy | Antrum | BabA (L vs H) | 0.86 ± 0.33 | .022 | 0.40 |
BabA (H vs negative) | 0.31 ± 0.41 | ||||
BabA (L vs negative) | 1.17 ± 0.49 | ||||
cagA (positive vs negative) | 0.69 ± 0.33 | .040 | |||
Corpus | BabA (L vs H) | 0.44 ± 0.18 | .007 | 0.42 | |
BabA (H vs negative) | 0.34 ± 0.25 | ||||
BabA (L vs negative) | 0.78 ± 0.27 | ||||
cagA (positive vs negative) | 0.52 ± 0.22 | .106 | |||
East Asia | |||||
H pylori density | Antrum | BabA (L vs H) | 0.68 ± 0.29 | .023 | 0.32 |
Corpus | BabA (L vs H) | 0.53 ± 0.29 | .067 | 0.38 | |
Neutrophil infiltration | Antrum | BabA (L vs H) | 0.85 ± 0.26 | .001 | 0.58 |
Corpus | BabA (L vs H) | 0.61 ± 0.27 | .029 | 0.40 | |
Atrophy | Antrum | BabA (L vs H) | 0.88 ± 0.32 | .006 | 0.48 |
Corpus | BabA (L vs H) | 0.48 ± 0.22 | .027 | 0.58 |
NOTE. In the analyses, the partial regression coefficient 0.77 of BabA (BabA-L vs BabA-H) for H pylori density can be interpreted as showing that the H pylori density score with BabA-L strains would be expected to be 0.77 points greater than with BabA-H strains.