Figure 2. A failure of lens development in N-cadherin mutants.
Micrographs show the eye region of E10.5 (A-J) or E12.5 (K-O) embryos of the indicated genotypes labeled for the markers as color-coded above or on the panels. The absence of lens development is apparent at E10.5 examples (F-J) and E12.5 (L, N, O). lv – lens vesicle, pr – presumptive retina, prpe – presumptive retina pigmented epithelium, ple – presumptive lens ectoderm, ov – optic vesicle, oc- optic cup.