Table 2.
Geometric Mean Antibody Concentrations according to Baseline Seropositivity and Anal HPV DNA Detection
| Anti-HPV Serology |
Anal HPV DNA detection |
n | Seropositive at week 28 (n, %) |
Baseline GMC (mMU/mL) |
Week 28 GMC (mMU/mL, 95% confidence interval) |
|
|---|---|---|---|---|---|---|
| Type 6 | ||||||
| Negative | Negative | 60 | 59 (98) | 6 | 357 | (256, 497) |
| Negative | Positive | 2 | 2 (100) | 7 | 47 | a |
| Positive | Negative | 32 | 30 (94) | 75 | 1050 | (514, 2143) |
| Positive | Positive | 6 | 6 (100) | 86 | 531 | (351, 804) |
| Type 11 | ||||||
| Negative | Negative | 68 | 67 (99) | 5 | 525 | (412, 669) |
| Negative | Positive | 3 | 2 (67) | 6 | 177 | a |
| Positive | Negative | 24 | 24 (100) | 46 | 1804 | (1263, 2576) |
| Positive | Positive | 5 | 5 (100) | 90 | 617 | (154, 2472) |
| Type 16 | ||||||
| Negative | Negative | 62 | 62 (100) | 6 | 1139 | (849, 1529) |
| Negative | Positive | 13 | 12 (92) | 6 | 504 | (177, 1434) |
| Positive | Negative | 19 | 19 (100) | 74 | 2067 | (1145, 3733) |
| Positive | Positive | 6 | 6 (100) | 117 | 1480 | (280, 7831) |
| Type 18 | ||||||
| Negative | Negative | 78 | 74 (95) | 5 | 181 | (136, 241) |
| Negative | Positive | 5 | 5 (100) | 5 | 183 | (27, 1248) |
| Positive | Negative | 14 | 14 (100) | 54 | 819 | (413, 1623) |
| Positive | Positive | 3 | 3 (100) | 63 | 840 | a |
a
Confidence intervals not reported for subgroups with <5 participants
GMC=Geometric Mean Concentration of anti-HPV antibodies; mMU/mL=milli-Merck units/mL