Table 2.
Combined genotype sets for the different states of the Markov chain, in a model with normal contamination γ. The weights for the respective combined genotypes are the Hardy-Weinberg weights as in the model without normal tissue contamination, and the total and minor copy numbers for the abberated components are as in Table 1.
| Statei | Combined genotype setGi |
|---|---|
| 1 | {2γA, γAγB, 2γB} |
| 2 | {(1 + γ)A, AγB, γAB, (1 + γ )B} |
| 3 | {2A, (2 − γ)AγB, γA(2 − γ)B, 2B} |
| 4 | {AA, AB, BB} |
| 5 | {(3 − γ)A, (3 − 2γ)AγB, γA(3 − 2γ)B, (3 − γ)B} |
| 6 | {(3 − γ)A, (2 − γ)AB, A(2 − γ)B, (3 − γ)B} |
| 7 | {(4 − 2γ)A, (4 − 3γ)AγB, γA(4 − 3γ)B, (4 − 2γ)B} |
| 8 | {(4 − 2γ)A, (3 − 2γ)AB, A(2 − γ)B, (4 − 2γ)B} |
| 9 | {(4 − 2γ)A, (2 − γ)A(2 − γ)B, (4 − 2γ)B} |
| 10 | {(5 − 3γ)A, (5 − 4γ)AγB, γA(5 − 4γ)B, (5 − 3γ)B} |
| 11 | {(5 − 3γ)A, (4 − 3γ)AB, A(4 − 3γ)B, (5 − 3γ)B} |
| 12 | {(5 − 3γ)A, (3 − 2γ)A(2 − γ)B, (2 − γ)A(3 − 2γ)B, (5 − 3γ)B} |
| 13 | {(6 − 4γ)A, (6 − 5γ)AγB, γA(6 − 5γ)B, (6 − 4γ)B} |
| 14 | {(6 − 4γ)A, (5 − 4γ)AB, A(5 − 4γ)B, (6 − 4γ)B} |
| 15 | {(6 − 4γ)A, (4 − 3γ)A(2 − γ)B, (2 − γ)A(4 − 3γ)B, (6 − 4γ)B} |
| 16 | {(6 − 4γ)A, (3 − 2γ)A(3 − 2γ)B, (6 − 4γ)B} |