Table 3.
IC50 determinations for haspin and DYRK2 kinase inhibition23
 | |||
|---|---|---|---|
| Compd | X | Haspin IC50 (μM) | DYRK2 IC50 (μM) |
| 12 | NH | 1.7 | 6.5 |
| 13 | O | NA | NA |
| 18 | CH2 | 0.025 | 0.24 |
NA: Not active at 20 μM.
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