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. Author manuscript; available in PMC: 2011 Jun 20.
Published in final edited form as: Clin Cancer Res. 2009 Feb 17;15(5):1534–1542. doi: 10.1158/1078-0432.CCR-08-1783

Table 1.

Frequency of lymphoma, myeloproliferation and other malignancies

Lymphoma Myelopro- liferation Other Malignancies* Myeloid Hyperplasia
1 WT Control 0/20(0) 0/20(0) 0/20(0) 0/20(0)
2 NQO2-Null Control 5/20(25) 0/20(0) 0/20(0) 18/20(90)
3 P<0.0281 P<0.9999 P<0.9999 P<0.0001
4 WT 1Gy 0/20(0) 0/20(0) 0/20(0) 0/20(0)
5 NQO2-Null 1Gy 8/19(42) 5/19(26) 6/19(32) 19/20(95)
6 P<0.0002 P<0.0001 P<0.0001 P<0.0001
7 WT 3Gy 2/19(11) 0/19(0) 0/19(0) 0/20(0)
8 NQO2-Null 3Gy 13/18(72) 4/18(22) 3/18(17) 18/20(90)
9 P<0.0001 P<0.0001 P<0.0205 P<0.0001
*

Most other malignancies were lung adenocarcinoma.

Numbers in parenthesis show the percentage of mice with lymphoma, myeloproliferation, other malignancies, and myeloid hyperplasia.

The experiments were setup in four groups and each group contained 5 animals. P values for WT and NQO2-Null control are shown in line 3. P values for WT 1Gy versus NQO2-Null 1Gy are shown in line 6. P values for WT 3Gy versus NQO2-Null are shown in line 9.