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. 2011 Apr 5;300(6):E1059–E1068. doi: 10.1152/ajpendo.00083.2011

Table 1.

Gene expression in adipose-depleted MECs following 8 h of BrCr treatment

Adipose-Depleted MECs
Functional Category Control BrCr Fold change
Milk protein genes
    Csn2 1.43 0.86 −1.65c
    Lalba 1.36 0.67 −2.01b
    Wap 1.10 0.88 N/C
Glycolysis and pentose shunt
    Glut1 1.95 0.54 −3.59c
    G6pd2 0.91 0.38 −2.43b
    AldoC 1.69 0.37 −2.93b
    Gapdh 1.24 0.55 −2.25c
    Me1 1.09 0.50 −2.16b
De novo fatty acid synthesis
    Slc25a1 1.69 0.37 −4.59a
    Acly 1.65 0.30 −5.45d
    Acc1α 1.44 0.22 −6.43d
    Fasn 1.08 0.34 −3.13b
    Thrsp 0.77 0.69 N/C
TAG synthesis and β-oxidation
    Dgat1 1.08 0.48 −2.24b
    Scd2 2.03 0.10 −19.46c
    Fads1 1.44 0.40 −3.62c
    Acaa2 0.50 0.52 N/C
    Acadl 0.46 0.63 N/C
Regulatory factors
    Akt1 2.55 0.92 −2.77c
    Prlr-Long 0.96 0.37 −2.60d
    Srebp1a 0.77 0.38 −2.05b
    Srebp1c 0.74 0.22 −3.34b

Gene expression in adipose-depleted mammary epithelial cells (MECs) following 8-h bromocriptine (BrCr) treatment. Genes are grouped into functional categories. Values are mean normalized transcript copy numbers for that gene using standard curve-based qRT-PCR; n = 5 mice per condition. Fold change is calculated as −1/(BrCr/Control). Statistical significance: aP ≤ 0.05, bP ≤ 0.01, cP ≤ 0.001, dP ≤ 0.0001. N/C, no statistical change, using Excel's t-test function.