FIG. 1.

Body weight of mice maintained on control and HFD. Body weights are presented for mice fed the control and HFD for up to 16 weeks. Weights were recorded every Friday afternoon during the 16-week feeding period. Results from repeated measure analysis of variance: diet, p = 0.36; time, p < 0.0001; interaction (diet vs. time), p = 0.26. Data represent the mean ± SEM for n = 8 animals per group. Note that these data are recorded from the same eight mice per treatment during the 16-week feeding protocol. HFD, high-fat diet; SEM, standard error of the mean.