Table 1.
Baseline values for parameters of continuous infusion CMGa
| Parameter | LY215490 (i.c.v.) | LY215490 (i.t.) | MK-801 (i.c.v.) | MK-801 (i.t.) | Vehicle+ LY215490 (i.c.v.) | MK-801+ LY215490 (i.c.v.) | Vehicle+ LY215490 (i.t.) | MK-801+ LY215490 (i.t.) | Total (n=40) |
|---|---|---|---|---|---|---|---|---|---|
| BCA (cm H2O) | 24.0±0.4 | 28.9±2.4 | 24.4±3.2 | 28.2±2.0 | 27.7±1.2 | 27.7±2.8 | 25.2±2.2 | 31.3±2.2 | 27.2±0.8 |
| ICI (s) | 137±62 | 121±37 | 56±14 | 100±33 | 65±11 | 74±21 | 62±9 | 52±9 | 83±11 |
| BCD (s) | 41±5 | 41±4 | 34±1 | 39±6 | 34±2 | 35±3 | 37±3 | 31±2 | 37±1 |
| EUS EMG (pulses/s) | 147±20 | 185±40 | 148±17 | 162±27 | 177±42 | 199±39 | 167±38 | 152±28 | 167±11 |
a
BCA, bladder contraction amplitude; BCD, bladder contraction duration; ICI, intercontraction interval.
All values are expressed as mean ± S.E.M (n=5 for each group).