Table 5.

Elimination of group A streptococci from the mucosal surface of colonized mice (500 units lysin/mouse)

Mouse	Strep (107) ↓	Day 1	Day 2	Day 3	Day 4	Lysin ↓	Postlysin treatment
							Day 4, 2 hr	Day 5, 24 hr	Day 6, 48 hr
1		>300	>300	>300	>300		0	0	200*
2		>300	>300	>300	>300		0	50*	0
3		>300	>300	>300	>300		0	0	0
4		>300	>300	>300	>300		0	0	0
5		>300	>300	>300	>300		0	Dead	Dead
6		>300	>300	>300	>300		0	n.d.	0
7		>300	>300	>300	>300		0	n.d.	0
8		>300	>300	>300	>300		0	n.d.	0
9		>300	>300	>300	>300		0	n.d.	0
Total colonized		9/9	9/9	9/9	9/9		0/9	2/5	2/9

n.d., no data collected; indicated numbers are cfus.. 

^*Isolated streptococci remained sensitive to lysin treatment in vitro.