Fig. 5.

Changes in A-type current during postnatal development. A: A-type current was isolated by subtracting current from a holding potential (HP) of −40 mV from current elicited after a brief (150 ms) prepulse to −70 mV to remove inactivation of A-type current. The protocol (bottom trace) and resulting currents (top trace) are shown. Trace at right is the subtracted trace for this example. B: examples of subtracted currents recorded from animals at 1 wk, 2 wk, 3 wk, and 4 wk of age. Biophysical separation was incomplete, especially at the later ages (see text).