Table 3. Glucose levels, insulin levels and HOMA75 in baseline and follow up study according to SNP distribution.
| Baseline study | Follow-up study | Incidence of HOMA75‡ | |||||
| Insu_120 | Gluc_120 | HOM75% (%) | Insu_120 | Gluc 120 | HOM75% (%) | (%) | |
| Rs3813825 | |||||||
| TT | 50±46 b | 118±32 ab | 33.7 b | 43±41 | 118±38 b | 38.5 | 28.3 |
| AT | 47±40 b | 116±32 b | 36.9 b | 38±31 | 114±32 b | 39.6 | 24.4 |
| AA | 77±53 a | 132±45 a | 60.0 a | 57±80 | 139±63 a | 53.1 | 33.3 |
| Rs17041272 | |||||||
| CC | 51±46 | 118±33 | 36.0 | 42±41 | 117±37 | 39.0 | 25.9* |
| CG | 50±34 | 120±33 | 34.9 | 45±38 | 123±44 | 47.1 | 38.9 |
| GG | 53±31 | 116±56 | 60.0 | 41±21 | 109±17 | 40.0 | |
| Rs4141123 | |||||||
| AA | 56±41 | 122±38 | 38.9 | 48±55 | 119±42 | 41.5 | 26.3 |
| AG | 52±45 | 117±31 | 38.7 | 40±37 | 118±39 | 39.3 | 25.6 |
| GG | 48±45 | 118±33 | 31.1 | 42±37 | 117±34 | 40.1 | 30.2 |
| Rs9997926 | |||||||
| CC | 50±45 | 118±33 | 35.6 | 43±40 | 119±38 | 42.1 a | 29.8* |
| CT | 52±47 | 117±33 | 34.0 | 38±34 | 117±40 | 29.9 b | 17.9 |
| TT | 66±30 | 130±21 | 60.0 | 89±103 | 122±32 | 40.0 ab | |
| Rs6824447 | |||||||
| AA | 52±45 | 119±34 | 40.7 | 42±34 | 119±35 | 44.9 | 32.8 |
| AG | 50±42 | 118±32 | 32.4 | 41±41 | 118±38 | 36.9 | 24.9 |
| GG | 52±50 | 118±34 | 36.4 | 45±47 | 118±40 | 40.4 | 25.5 |
‡Persons who had HOMA IR below the 75th percentile and without type 2 diabetes at the baseline study and who had HOMA IR above the 75th percentile six years later.
Insu_120 = insulin at 120 min after an oral glucose load; Gluc_120 = glucose at 120 min after an oral glucose load.
*P<0.05. Chi_square test.
Values with different letters are significantly different (P<0.05). ANOVA test.
Insulin (µU/ml), glucose (mg/dl).