Table 2. Comparison of genotype calls by SNP 6 chip and exome sequencing.
All SNP | homozygous SNP | heterozygous SNP | |||||||
cell-line | all SNP | same genotype call | percent | homozygous SNP | same genotype call | percent | heterozygous SNP | same genotype call | percent |
A2780 | 29193 | 25493 | 87% | 22079 | 21559 | 98% | 7114 | 3934 | 55% |
A549 | 26407 | 24065 | 91% | 22627 | 22188 | 98% | 3780 | 1877 | 50% |
Colo205 | 27638 | 24780 | 90% | 23526 | 22797 | 97% | 4112 | 1983 | 48% |
GTL16 | 29650 | 27474 | 93% | 26447 | 25691 | 97% | 3203 | 1783 | 56% |
NCI-H661 | 29117 | 26901 | 92% | 26737 | 25756 | 96% | 2380 | 1145 | 48% |
MDA-MB468 | 29360 | 27088 | 92% | 25914 | 25221 | 97% | 3446 | 1867 | 54% |
PC3 | 27914 | 25505 | 91% | 24421 | 23729 | 97% | 3493 | 1776 | 51% |
RD | 28594 | 26154 | 91% | 24616 | 23870 | 97% | 3978 | 2284 | 57% |
Average | 28484 | 25933 | 91% | 24546 | 23851 | 97% | 3938 | 2081 | 52% |