Table 3. Coefficient estimates from AIC-selected linear models of baseline 
and 
plasma HIV RNA on position-specific SDRMs and demographic and risk factors.
|
 plasma HIV RNA |
|||
| Estimate (95% CI) |
 value |
Estimate (95% CI) |
 value |
|
| M41X | 1.0 (0.05, 1.95) | 0.04 | NS | |
| M46X | NS |
 ( ,  ) |
0.003 | |
| D67X |
 ( ,  ) |
|
0.96 (0.25, 1.7) | 0.009 |
| M184X | NS |
 ( ) |
|
|
| L210X | NS |
 ( ,  ) |
0.007 | |
| K219X |
 ( ,  ) |
|
NS | |
| D67X:K219X |
 ( ,  ) |
|
 ( ,  ) |
0.047 |
| K219X:G190X |
 ( ,  ) |
|
NS | |
| L90X:M41X |
 ( ,  ) |
|
NS | |
| I54X:L210X |
 ( ,  ) |
|
NS | |
| M46X:T215X | NS | 1.7 (0.88, 2.5) | 0.033 | |
| M184X:K103X | NS | 0.58 ( 0.14, 1.3) |
0.018 | |
| M184X:K219X | NS | 0.87 ( 0.07, 1.8) |
0.023 | |
| K219X:Y181X | NS | 1.43 (0.34, 2.5) | 0.013 | |
| Male |
 ( ,  ) |
|
NS | |
| Sample date | 23.3 (7.4, 38.9) 
|
|
 ( ,  ) 
|
0.04 |
| Race/ethnicity | ||||
| Black |
 ( ,  ) |
|
 ( ,  ) |
0.003 |
| Hispanic |
 ( ,  ) |
|
NS | |
| other |
 ( ,  ) |
|
NS | |
SDRMs are annotated by HXB2 reference residue and position (gene-specific numbering), followed by an ‘X’ to indicate a non-reference residue. Positions 46, 54, and 90 are in protease and all others are in reverse transcriptase. All estimates were averaged over an ensemble of linear models using Akaike weights. Only terms that were statistically significant (
) are reported here. NS = not significant.