Figure 3. Tissue specific nature of Cre recombinase expression and lack of effect on Cu, Zn SOD protein expression.
Representative immunohistochemistry micrographs of liver, heart, and kidney sections from Kidney Cre, 50% KO and 100% KO mice (n = 6). Sections were evaluated for Cre recombinase (a-f; heart and liver), MnSOD (g-l; heart and liver), and Cu, Zn SOD (m-o; kidney) protein expression. Representative bars indicate 50 μm for 400× images (a-l) and 500 μm for 40× images (m-o).