Table 1. Differential changes in the promoter methylation status of various cytokine-producing genes in response to Porphyromonas gingivalis vs. Fusobacterium nucleatum.

Bacteria	Increased methylation	Decreased methylation
P. gingivalis	CD276 (P<0.005) ELA2 (P<0.01) INHBA (P<0.01) GATA3 (P<0.005) TLR2 (P<0.005) IL-12A (P<0.005)	ZNF287 (P<0.05) STAT5A (P<0.005)
F. nucleatum	MALT1	ELA2 (P<0.005) GATA3 (P<0.01)

Abbreviations: ELA2, elastase 2, neutrophil; GATA3, GATA binding protein 3; IL-12A, interleukin 12A; INHBA, inhibin, β; MALT1, mucosa associated lymphoid tissue lymphoma translocation gene 1; STAT5A, signal transducer and activator of transcription 5A; TLR2, Toll-like receptor 2; ZNF287, zinc-finger protein 287.