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. 2001 Mar 27;98(7):4119–4124. doi: 10.1073/pnas.051004198

Figure 7.

Figure 7

Determination of elements in the Lyta promoter region. (A) Schematic diagram of the Lyta promoter and a series of nested deletion mutants. Numbers indicate the position relative to the transcription start site of Lyta (7). A hypermethylated region is shown in the promoter region between −315 to −255 base. Closed circles: methylated CpGs in latently infected KSHV. (B) Luciferase activation of the Lyta promoter and the corresponding deletion mutants. Rev.: Promoter orientation-reverse construct.