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. 2011 May 30;11:212. doi: 10.1186/1471-2407-11-212

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Copyright ©2011 Hamma-Kourbali et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Induction of apoptosis in xenograft tumour by P111-136. PC-3 tumour apoptosis was evaluated on tumour sections using immunohistochemistry with antibody directed against cleaved caspase 3. (A), untreated tumours and (B), tumours treated with P111-136. Scale bar, 100 μm. (C), apoptosis quantified by image analysis of caspase 3-labelled cells on the whole tumour sections. The data are mean areas +/- SD obtained from 5 control mice and 5 mice treated with P111-136. **p < 0.01 versus control.