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Inhibition of tumour angiogenesis by peptide P111-136. For immunohistochemical analysis, tumour sections were prepared and stained with anti-CD31 antibodies. (A), untreated tumours and (B), tumours treated with P111-136. Scale bar, 100 μm. (C), angiogenesis was quantified by image analysis of CD31-labelled endothelial cells. The data are mean areas +/- SD obtained from 5 control mice and 5 mice treated with P111-136. **p < 0.01 versus control.
