Figure 2. Anxiety-like Behavior is decreased in chronically socially isolated mice compared to group housed mice.
A. Time spent on the open arm of the EZM (seconds). All mice were tested after being group housed or socially isolated for 24 hours or 5–6 weeks. Chronic socially isolated mice spent significantly less time in the open arm of the EZM compared to group housed mice (n=7–13 per group), *p<0.05. Data are represented as mean ± SEM.
B. Number of open arm entries on the EZM. No significant differences were found on number of open arm entries. (n=7–13 per group). Data are represented as mean ± SEM.
C. Time spent in the center zone of the NOF. Chronic socially isolated mice spent significantly less time in the center zone of the NOF compared to group housed mice (n=7–13 per group), *p<0.05. Data are represented as mean ± SEM.
D. Distance Traveled on the NOF. No differences were found in the distance traveled on the NOF. (n=7–13 per group). Data are represented as mean ± SEM.