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. 2011 May 11;2011:659704. doi: 10.1155/2011/659704

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Copyright © 2011 Hong Zeng et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Microbiological study of the therapeutic efficacy of essential oil versus FCZ against vaginal candidiasis in mice. Outcome of vaginal infection by C. albicans 09-1555 in immunosuppressed BALB/c mice inoculated intravaginally with essential oil and FCZ. CK: negative control group (no Candida was found in the vaginal lumina). Group 1: infected, untreated but not immunosuppressed animals. Group 2: positive control group, immunosuppressed, inoculated intravaginally with C. albicans 09-1555, received excipient. Group T1: treated groups: immunosuppressed, infected animals that received FCZ (20 μL at 100 μg/mL). Groups T2, T3, T4: treated groups: immunosuppressed, infected animals that received essential oils (20 μL at 2, 1, and 0.0625% v/v). The value log cfu was showed by the mean ± S.E.M. (n = 6). **: compared with Group 2 (P < .01); *: compared with Group 2 (P < .05).