Skip to main content
. 2011 Jun 20;6(6):e21077. doi: 10.1371/journal.pone.0021077

Figure 2. GYY4137 but not NaHS significantly affected cancer cell survivability.

Figure 2

(A) The effect of treatment (5 days) of a range of cancer and non-cancer cells with NaHS, GYY4137 and ZYJ1122 (400 µM or 800 µM) as determined by trypan blue staining. Results show percentage of cell viability to non-treatment (NT) following incubation in the absence of drug treatment and are mean ± s.e. mean, n = 3, (# P<0.05; *P<0.01). (B) Concentration-response curves showing the effect of GYY4137 treatment for 5 days on survival of MCF-7, HL-60 and MV4-11 cells. Results show mean ± s.e. mean, n = 3. (C) Representative photographs showing clonogenic survival assays of MCF-7 cells following exposure (5 days, 200–600 µM) to either NaHS (top row), GYY4137 (middle row) and ZYJ1122 (bottom row). NT =  non-treatment.