Table 3.

Mean and standard deviation of Jaccard overlap ratio computed across subjects for comparisons of affine, LDDMM-image, and 6D-LDDMM. Bold typesetting indicates that Jaccard overlap ratio for 6D-LDDMM is statistically significantly higher than that of affine and LDDMM-image (p<0.0001).

	Affine	LDDMM-image	6D-LDDMM
Left-white matter	0.4638 (0.04)	0.7325 (0.02)	0.7948 (0.02)
Left-cortex	0.3414 (0.02)	0.6490 (0.03)	0.7659 (0.02)
Left-lateral ventricles	0.3691 (0.13)	0.8048 (0.05)	0.7983 (0.05)
Left-thalamus	0.5660 (0.13)	0.6982 (0.06)	0.6915 (0.06)
Left-caudate	0.3645 (0.20)	0.6539 (0.06)	0.6789 (0.05)
Left-putamen	0.4870 (0.10)	0.7073 (0.04)	0.7104 (0.05)
Left-pallidum	0.4161 (0.12)	0.6409 (0.06)	0.6372 (0.08)
Left-hippocampus	0.4401 (0.10)	0.5509 (0.11)	0.5516 (0.10)
Left-amygdala	0.3908 (0.10)	0.5886 (0.07)	0.5982 (0.08)
Right-white matter	0.4701 (0.03)	0.7331 (0.02)	0.7985 (0.01)
Right-cortex	0.3541 (0.02)	0.6471 (0.03)	0.7753 (0.02)
Right-lateral ventricles	0.3744 (0.12)	0.7898 (0.05)	0.7854 (0.06)
Right-thalamus	0.6177 (0.10)	0.7351 (0.04)	0.7331 (0.04)
Right-caudate	0.3553 (0.19)	0.6474 (0.06)	0.6638 (0.06)
Right-putamen	0.5226 (0.09)	0.7130 (0.03)	0.7032 (0.04)
Right-pallidum	0.4477 (0.12)	0.6352 (0.07)	0.6314 (0.08)
Right-hippocampus	0.4028 (0.10)	0.5730 (0.11)	0.5614 (0.11)
Right-amygdala	0.3929 (0.09)	0.5583 (0.09)	0.5647 (0.08)