Figure 2. Morphometry of newborn CFTRΔF508/ΔF508 trachea.
A. Cross section of trachea. MT stain. Bars=1 mm. Images from CFTR+/+ and CFTR−/− are from reference (29).
B–E. Tracheal morphometry in CFTR+/+ (n=20), CFTRΔF508/ΔF508 (n=19), and CFTR−/− (n=18) newborn pigs. * indicates different from CFTR+/+ and # indicates different from CFTR−/− (* P<0.05 vs. CFTR+/+, and # P<0.05 vs. CFTR−/−, 1-way ANOVA with Bonferroni’s post test).
B. Tracheal lumen cross-sectional area.
C. Tracheal circumference.
D. Submucosal gland area normalized to tracheal lumen circumference.
E. Smooth muscle area normalized to tracheal lumen area.