Table 2.
Cardiac tissue omega-3 polyunsaturated fatty acid content
| EPA | DHA | Omega-3 Index | |
|---|---|---|---|
| Right atrium | |||
| placebo (n = 12) | 0.32 ± 0.11 | 0.56 ± 0.14 | 0.85 ± 0.22 |
| 1 g/day (n = 6) | 1.24 ± 0.11* | 3.38 ± 0.20* | 4.63 ± 0.18* |
| 2 g/day (n = 12) | 1.45 ± 0.23* | 2.89 ± 0.41* | 4.34 ± 0.64* |
| 4 g/day (n = 22) | 2.76 ± 0.44* | 3.54 ± 0.50* | 6.31 ± 0.88* |
| Sham (n = 5) | 2.80 ± 0.43* | 3.83 ± 0.23* | 6.63 ± 0.31* |
| Left ventricle | |||
| placebo (n = 12) | 0.31 ± 0.06 | 0.49 ± 0.08 | 0.80 ± 0.11 |
| 1 g/day (n = 6) | 1.25 ± 0.09* | 3.08 ± 0.17* | 4.33 ± 0.21* |
| 2 g/day (n = 12) | 1.69 ± 0.20* | 2.67 ± 0.21* | 4.35 ± 0.64* |
| 4 g/day (n = 22) | 3.81 ± 0.30* | 3.43 ± 0.20* | 7.24 ± 0.45* |
| Sham (n = 5) | 3.71 ± 0.43* | 3.65 ± 0.28* | 7.07 ± 0.70* |
All values are means ± SE and are expressed as %total lipid content. Sham (i.e., no myocardial infarction) received 4 g/day; EPA = eicosapentaenoic acid; DHA = docasahexaenoic acid; omega-3 index = EPA + DHA.
*
P < 0.01, omega-3 treated vs. placebo.