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. 2011 Mar 18;300(6):H2177–H2186. doi: 10.1152/ajpheart.01138.2010

Fig. 7.

Fig. 7.

Mitochondrial Bax protein levels and ROS production are associated with mitochondrial PTEN protein levels in mouse hearts. A: PTEN was overexpressed in WT hearts by adenoviral Pten (adPten) transfer. Empty vectors (adNull) were used as controls. PTEN and Bax protein levels were analyzed in mitochondrial fractions. B: mitochondrial PTEN and Bax protein levels were measured in muscle-specific PKO and control mouse hearts. C and D: ROS production was measured in adPten and adNull (C) and PKO and control (D) hearts by a DHF fluorescence assay. n = 3. *P < 0.05, adPten vs. adNull hearts; †P < 0.05, PKO vs. control hearts.