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Nuclear factor of activated T cell (NFAT)-dependent luciferase activity of Ryr2+/+, Ryr2+/ADA, and Ryr2ADA/ADA mice. NFAT-dependent promoter driven luciferase activity was determined in hearts carrying NFAT-luciferase transgene as described in materials and methods. Luciferase activities of E16.5, 1-day-old, and 10-day-old mice were normalized to age-matched WT littermates. Data are means ± SE of 5 to 11 hearts. *P < 0.01 compared with WT at same age.
