. 2011 Mar 18;300(6):H2187–H2195. doi: 10.1152/ajpheart.00719.2010

Table 2.

Echocardiography of 10-day-old WT and mutant mice

	Ryr2^+/+		Ryr2^ADA/ADA
Parameters	CNA-β^+/+	CNA-β^−/−	CNA-β^+/+	CNA-β^−/−
HR, beats/min	589 ± 21	607 ± 18	490 ± 18^*^†	479 ± 4^*^†
LVEDD, mm	1.59 ± 0.11	1.44 ± 0.06	3.28 ± 0.24^*^†	2.46 ± 0.17^*^†^‡
LVESD, mm	0.68 ± 0.06	0.67 ± 0.06	2.96 ± 0.25^*^†	1.94 ± 0.15^*^†^‡
FS, %	57.0 ± 2.0	54.2 ± 2.8	10.3 ± 1.3^*^†	21.4 ± 0.9^*^†^‡
IVSD, mm	0.83 ± 0.07	0.80 ± 0.07	0.84 ± 0.06	0.67 ± 0.08
IVSS, mm	1.21 ± 0.07	1.21 ± 0.07	0.97 ± 0.06	0.90 ± 0.11^*
LVPWD, mm	0.95 ± 0.04	0.73 ± 0.06	0.83 ± 0.08	0.81 ± 0.06
LVPWS, mm	1.28 ± 0.05	0.96 ± 0.09^*	0.90 ± 0.09^*	1.03 ± 0.09

Values are means ± SE; n = 8, 5, 7, and 4 mice for Ryr2^+/+/CNA-β^+/+, Ryr2^+/+ /CNA-β^−/−, Ryr2^ADA/ADA/CNA-β^+/+, and Ryr2^ADA/ADA/CNA-β^−/− groups, respectively.

P < 0.05 compared with Ryr2^+/+/CNA-β^+/+;

^†

P < 0.05 compared with Ryr2^+/+/CNA-β^−/−;

^‡

P < 0.05 compared with Ryr2^ADA/ADA/ CNA-β^+/+.