Figure 4.

(A) Schematic representation of full-length msp2 compared with the msp2 pseudogenes. Numbering of full-length msp2 is indicated in base pairs and amino acids. The hypervariable region is indicated by stippling. (B) The deduced amino acid sequences of the msp2 pseudogenes obtained in this study are shown in comparison to the full-length msp2 sequence. The 5′ and 3′ conserved regions are on a gray background and flank the hypervariable region. The full-length pCKR11.2 continues for 134 aa (not shown). Pseudogenes 1 and 2 are from an A. marginale St. Maries strain, pseudogene 3 is from an A. marginale Florida strain (8), and the remaining pseudogenes are from an A. marginale South Idaho strain and are lettered A-D as denoted in Fig. 3.