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Effect of occludin siRNA in mouse small intestine permeability in vivo. A: occludin siRNA transfection in mouse intestine caused a significant increase in Texas red-labeled dextran (10 kDa) flux (means ± SE, n = 4). *P < 0.001 vs. control. B: occludin siRNA transfection did not affect the electrical resistance of small intestine tissue mounted on an Ussing chamber (means ± SE, n = 6).
