Fig. 2.

Lung weight-to-body weight ratios (lung weight/body weight) at 3 and 7 days post-PNX or THX. The ratio of right lung weight to whole body weight (lung weight/body weight) was calculated for pneumonectomized or sham-operated mice at POD3 (THX and PNX groups) or POD7 (PNX only), and the resulting values were each multiplied by 100. By Student's t-test, the difference in lung weight/body weight for WT mice at PNX POD7 was significant compared with the ratio for THX samples (*P = 0.0019) and also significant compared with the ratio for terc^−/− 3rd generation (F3) PNX at the same time point (**P = 0.0026). No significant difference was noted when ratios for terc^−/−F3 THX and PNX POD7 were compared (P = 0.2746; n = 3–8 for all groups).