Fig. 6.
Correlation between the degree of oxidative stress/endothelial dysfunction and the degree of RVH [RV-to-left ventricle ratio (RV/LV)]. A: ROS productions normalized by their baseline values in various measurements [dihydroethidium (DHE), EPR, L012-enhanced chemiluminescence] correlates to RV/LV. B: expressions of p47phox, NOX1, NOX2, and NOX4 correlates to RV/LV. C: maximal endothelium-dependent relaxation correlates inversely to RV/LV. D: blood flow (Q̇) of RCA correlates directly to RV/LV, which indicates that blood flow in RCA increases proportionally to RV growth during RVH. Values are means ± SD.