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Whole kidney glomerular filtration rate in Sham-control (left) and ANG II (right) groups at baseline, during PPADS, coadministration of l-NAME+PPADS, and l-NAME alone. Values are means ± SE. *P < 0.01 vs. Sham-vehicle. ΔP < 0.01 vs. ANG II+vehicle. ○P < 0.001 vs. Sham+PPADS; ●P < 0.001 vs. ANG II+PPADS. □P < 0.001 vs. Sham+l-NAME+PPADS. ■P < 0.001 vs. ANG II+l-NAME+PPADS. ◊P < 0.001 vs. Sham+l-NAME. ♦ P < 0.01 vs. ANG II+l-NAME.
