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Dramatic upregulation of RYR in a subset of fibers in a subset of rats
| CIM Rat No. | Number of Fibers with Dramatic Upregulation of RYR | No. of Normal Fibers |
|---|---|---|
| 1 | 13 | 130 |
| 2 | 0 | 157 |
| 3 | 1 | 181 |
| 4 | 0 | 162 |
| 5 | 15 | 151 |
| 6 | 1 | 124 |
| 7 | 2 | 149 |
Count of fibers with elevated levels of RYR on immunostained longitudinal sections of tibialis anterior muscle. Fisher's exact test revealed that there was a statistically significant difference in the %abnormal fibers between rats (P < 0.0001).
