Table 3.

Serum hormone and metabolite data obtained during terminal bleed (days 173–179)

	DIO-AL, n = 7	DIO-WR, n = 8	CON-AL, n = 8	CON-WR, n = 8
Leptin, ng/ml	121.7 ± 14.9a	25.1 ± 2.9b	14.0 ± 3.6b*	9.0 ± 1.3b*
Insulin, μg/l	3.7 ± 0.7a	1.6 ± 0.2b	1.2 ± 0.2b	0.6 ± 0.1b
Glucose, mg/dl	125 ± 3a	105 ± 3b	110 ± 3b	94 ± 2c
T3, ng/dl	31.6 ± 5.3a	16.8 ± 1.8b	31.8 ± 8.1a	15.7 ± 4.4b
T4, ng/ml	45.8 ± 4	49.9 ± 2	46.1 ± 2.2	50.6 ± 2.6
TSH, ng/ml	283.1 ± 30.5	252.8 ± 35.5	221.7 ± 52.7	226.8 ± 42.6
HOMA2 S	10.1 ± 1.2a	24.3 ± 4.3ab	30.6 ± 4.5b	60.2 ± 11.2c
HOMA2 IR	11.1 ± 1.8a	4.9 ± 0.7b	3.8 ± 0.6bc	2.0 ± 0.3c

Data are means ± SE. T3, triiodothyronine; T4, thyroxine; TSH, thyroid-stimulating hormone; HOMA S, HOMA insulin sensitivity; HOMA IR, HOMA insulin resistance. Data not marked by the same letter are significantly different by 2-way ANOVA with Tukey's post hoc analysis.

^*Student's t-test comparisons of CON-AL and CON-WR against DIO-WR.