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. 2011 May 31;11:63. doi: 10.1186/1471-2377-11-63

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Copyright ©2011 Chen et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Summarized muscle ultrastructural findings of the four cerebrotendinous xanthomatosis cases. 1a. subsacrolemmal accumulation of mitochondria (arrow), (bar = 1 μm); 1b. mitochondria change in shape and enlarged in size (arrow), (bar = 1 μm); 1c. increased amount of lipid droplets (arrow), (bar = 2 μm); 1d. lipofuscin (arrow), (bar = 1 μm); 1e. triads proliferation (arrow), (bar = 1 μm); 1f. swollen sacroplasmic reticulum (arrow), (bar = 1 μm); 1g. laminated bodies (arrow), (bar = 0.5 μm); 1 h. membranous-like debris (arrow) in the subsacrolemmal space, (bar = 1 μm); 1i. increased amount of glycogen (marked as G, bar = 0.5 μm).