Table 2.
SNP | rs2808630 | rs1205 | rs1800947* | rs3093058 | rs3093066 | rs1417938 | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Location | 3' flanking region | 3' flanking region | Exon 2 | 5' flanking region | 5' flanking region | Intron 1 | ||||||||||||
Genotypes | AA | AG | GG | GG | AG | AA | GG | CG | CC | AA | AT | TT | CC | AC | AA | AA | AT | TT |
Non-Hispanic Whites | ||||||||||||||||||
N | 270 | 221 | 43 | 241 | 236 | 57 | 475 | ** | ** | 537 | 5 | - | 498 | 9 | - | 259 | 239 | 48 |
CKD, GFP | 50.75 | 42.68 | 6.57 | 46.17 | 42.19 | 11.63 | 93.19 | ** | ** | 98.36 | 1.64 | - | 97.69 | 2.31 | - | 47.44 | 43.7 | 8.79 |
N | 867 | 686 | 133 | 694 | 808 | 190 | 1544 | ** | ** | 1718 | 6 | - | 1610 | 15 | - | 851 | 730 | 148 |
No-CKD,GFP | 52.13 | 40.38 | 7.49 | 42.16 | 46.51 | 11.33 | 94.43 | ** | ** | 99.55 | 0.45 | - | 98.94 | 1.06 | - | 49.22 | 42.22 | 8.56 |
Non-Hispanic Blacks | ||||||||||||||||||
rs2808630 | rs1205 | rs1800947* | rs3093058 | rs3093066 | rs1417938 | |||||||||||||
N | 181 | 96 | 8 | 190 | 86 | 9 | ** | ** | - | 212 | 71 | 8 | 154 | 105 | 15 | 221 | 62 | ** |
CKD, GFP | 61.45 | 36.4 | 2.14 | 67.06 | 29.39 | 3.55 | 99 | ** | - | 76.01 | 22.89 | 1.1 | 56.35 | 38.37 | 5.28 | 77.75 | 20.65 | ** |
N | 950 | 323 | 26 | 804 | 397 | 79 | ** | ** | - | 915 | 356 | 34 | 751 | 443 | 67 | 1024 | 272 | 21 |
No-CKD,GFP | 72.24 | 25.42 | 2.34 | 62.68 | 31.26 | 6.06 | 99 | ** | - | 69.67 | 27.66 | 2.67 | 60.67 | 34.12 | 5.21 | 77.54 | 21.75 | 0.4 |
Mexicans Americans | ||||||||||||||||||
rs2808630 | rs1205 | rs1800947* | rs3093058 | rs3093066 | rs1417938 | |||||||||||||
N | 167 | 89 | 11 | 102 | 137 | 31 | 253 | 7 | - | 260 | 8 | ** | 269 | ** | ** | 110 | 130 | 24 |
CKD, GFP | 61.12 | 33.75 | 5.13 | 42.21 | 47.09 | 10.70 | 97.66 | 2.3 | - | 95.81 | 3.91 | ** | 99.25 | ** | ** | 41.67 | 49.23 | 9.1 |
N | 852 | 434 | 57 | 562 | 621 | 168 | 1266 | 54 | - | 1348 | 37 | ** | 1308 | ** | ** | 591 | 616 | 155 |
No-CKD,GFP | 62.48 | 33.04 | 4.48 | 41.65 | 45.65 | 12.7 | 95.6 | 4.4 | - | 97.08 | 2.92 | ** | 96.59 | ** | ** | 43.39 | 45.23 | 11.3 |
** Data user agreement with the CDC does not allow outputs with counts less than 5.
N: number of individuals with the specific genotype. GFP: genotype frequency percent