Table 5.
linear regression to eGFR (log transformed) for each SNP | ||||||
---|---|---|---|---|---|---|
Non-Hispanic Whites | Non-Hispanic Blacks | Mexican Americans | ||||
β(95% CI) | ¥ p-value | β (95% CI) | ¥ p-value | β(95% CI) | ¥ p-value | |
rs2808630 | ||||||
Unadjusted | -0.001 (-0.02, 0.01) | 0.55 | -0.01 (-0.04,0.02) | 0.61 | -0.01 (-0.01, 0.03) | 0.54 |
Fully adjusted | -0.01 (-0.04, 0.02) | 0.46 | 0.00 (-0.04, 0.04) | 0.94 | 0.01 (-0.01, 0.04) | 0.20 |
rs1205 | ||||||
Unadjusted | -0.001 (-0.02, 0.01) | 0.76 | -0.01 (-0.03, 0.02) | 0.53 | -0.001(-0.01, 0.02) | 0.55 |
Fully adjusted | -0.001 (-0.02, 0.02) | 0.84 | -0.01 (-0.04, 0.01) | 0.32 | 0.01 (-0.02, 0.04) | 0.55 |
rs1417938 | ||||||
Unadjusted | 0.001 (-0.02, 0.02) | 0.72 | -0.01(-0.04, 0.02) | 0.54 | -0.01 (-0.03, 0.01) | 0.51 |
Fully adjusted | 0.01 (-0.01, 0.03) | 0.35 | -0.02 (-0.05, 0.01) | 0.18 | -0.001(-0.03, 0.03) | 0.84 |
rs1800947 | ||||||
Unadjusted | -0.001 (-0.05, 0.04) | 0.87 | 0.01 (-0.13, 0.16) | 0.84 | 0.03 (- 0.02, 0.07) | 0.26 |
Fully adjusted | 0.01(-0.07, 0.09) | 0.75 | 0.04 (-0.20, 0.27) | 0.75 | 0.01 (-0.04, 0.06) | 0.72 |
rs3093058 | ||||||
Unadjusted | -0.08 (-0.31, 0.14) | 0.45 | 0.01 (-0.01, 0.04) | 0.36 | 0.01 (-0.05, 0.06) | 0.78 |
Fully adjusted | -0.04 (-0.13, 0.05) | 0.36 | -0.01 (-0.04, 0.02) | 0.63 | -0.03 (-0.11, 0.04) | 0.34 |
rs3093066 | ||||||
Unadjusted | 0.02 (-0.19, 0.23) | 0.86 | 0.02 (-0.01, 0.04) | 0.16 | -0.03 (-0.09, 0.03) | 0.37 |
Fully adjusted | 0.06 (-0.13, 0.25) | 0.53 | 0.01 (-0.02, 0.03) | 0.68 | -0.01 (-0.11, 0.08) | 0.78 |
¥ Unadjusted for multiple comparisons
Fully adjusted: age, gender, diabetes, hypertension, cardiovascular disease, BMI, smoking, LDL cholesterol, log transformed C reactive protein and albuminuria