Table 5.
Results of multivariate analysis of the relationship of PCB groupings to cognitive outcomes (n = 203 – 230)*.
| ΣDioxin-like PCBs50%a,b | ΣNondioxin-like PCBs50%a,b | ΣPersistent PCBs50%a,b | ΣLow-persistent PCBs50%a,b | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Std. β | p | r2 | Std. β | p | r2 | Std. β | p | r2 | Std. β | p | r2 | ||
| Ravens (RPM) | −0.16 | 0.04 | 17.5% | −0.08 | 0.30 | 17.4% | −0.14 | 0.14 | 16.3% | −0.06 | 0.40 | 16.3% | |
| TOMAL: | |||||||||||||
| Verbal Memory (VMIS) | −0.02 | 0.77 | 11.0% | −0.10 | 0.22 | 11.0% | −0.15 | 0.13 | 11.1% | −0.05 | 0.45 | 11.1% | |
| Nonverbal Memory (NMIS) | −0.05 | 0.57 | 11.3% | −0.07 | 0.41 | 11.3% | −0.08 | 0.38 | 11.3% | −0.05 | 0.50 | 11.3% | |
| Delayed Recall (DRIS) | −0.16 | 0.04 | 12.5% | −0.21 | 0.01 | 12.5% | −0.22 | 0.02 | 12.6% | −0.16 | 0.02 | 12.6% | |
| Composite Memory (CMIS) | −0.04 | 0.63 | 14.3% | −0.10 | 0.23 | 14.3% | −0.14 | 0.15 | 14.4% | −0.06 | 0.40 | 14.4% | |
| Woodcock Johnson (WJ-R): | |||||||||||||
| Broad Cognitive Ability Extended (BCAE) | −0.08 | 0.34 | 17.9% | −0.11 | 0.20 | 17.9% | −0.14 | 0.14 | 18.2% | −0.08 | 0.30 | 18.2% | |
| Long Term Retrieval (LTR) | −0.16 | 0.04 | 11.3% | −0.25 | 0.00 | 11.3% | −0.20 | 0.03 | 11.5% | −0.22 | 0.00 | 11.5% | |
| Short Term Memory (STM) | 0.06 | 0.43 | 13.1% | 0.00 | 0.97 | 13.1% | −0.04 | 0.64 | 13.0% | 0.04 | 0.62 | 13.0% | |
| Processing Speed (PSD) | 0.00 | 0.95 | 26.5% | −0.02 | 0.79 | 26.5% | −0.06 | 0.49 | 26.7% | 0.00 | 1.00 | 26.7% | |
| Auditory Processing (APG) | −0.14 | 0.09 | 11.0% | −0.13 | 0.13 | 11.1% | −0.23 | 0.02 | 12.2% | −0.08 | 0.27 | 12.2% | |
| Visual Processing (VPG) | −0.07 | 0.41 | 11.7% | −0.09 | 0.25 | 11.7% | −0.04 | 0.69 | 12.3% | −0.11 | 0.13 | 12.3% | |
| Comprehension-Knowledge (CKN) | −0.14 | 0.08 | 16.0% | −0.15 | 0.06 | 16.0% | −0.15 | 0.12 | 16.1% | −0.15 | 0.05 | 16.1% | |
| Fluid Reasoning (FRG) | −0.05 | 0.52 | 17.8% | 0.06 | 0.48 | 17.8% | −0.07 | 0.43 | 17.8% | −0.04 | 0.58 | 17.8% | |
*
Covariates included in the analysis are: Sex; age (yrs);adolescent and maternal BMI (kg/m2); adolescent triglyceride and cholesterol levels; maternal Broad Cognitive Ability Standard score; SES index; # reported social problems; gravidity; cigarette use during pregnancy; breast feeding duration (wks); p,p’ -DDE; HCB; Pb; Hg; mirex, and the converse PCB congener group.
a
Values below the mdl were calculated following the EPA recommended method for estimating non-detected values as described in Schell et al., 2003.
b
Orthogonal transformation was applied to all PCB grouping variables
Bold denotes p<0.05.