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. 2001 Mar 20;98(7):4142–4147. doi: 10.1073/pnas.041490898

Figure 3.

Figure 3

Electrophoretic analysis of PrPres of vCJD, BSE, sCJD, iCJD, and scrapie transmitted to C57BL/6 mice. Western blot detection of PrPres purified from the brains of C57BL/6 mice at the terminal stage of the disease (except for the control) after inoculation of normal mouse brain homogenate (lane 1); French case of iCJD linked to the administration of growth hormone (lane 2); French case of sCJD (lane 3); first of the three French vCJD cases (lane 4); cattle-BSE (lane 5); and natural sheep scrapie (French Romanov flock) (lane 6). The mouse brain equivalent loads were 0.6 mg (lanes 4 and 6), 1.2 mg (lanes 3 and 5), and 12 mg (lanes 1 and 2).